Tailored FFPE Reference Standards curl/block
Commutable FFPE Controls to mimic patient samples
Tailored to your needs
Formalin Fixed Paraffin Embedded Reference Standards. This products are developed/manufactured exclusively for you.
Human or animal cell line derived, based on your needs.
Regulatory status:
Available in Research Use Only or CE-IVD grade including technical documentation.
This quality control product is ideally suited as reference material in clinical genomics workflows. In particular:
– Validation and development of extraction protocols
– control in sequencing protocols (e.g. Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES), Amplicon Sequencing) and PCR protocols
– Determination of the detectiont limit of a method
– Calibration and development of instruments and workflows in DNA processing (e.g. DNA fragmentation via acoustic shearing, enzymatic digestion or sonication)
– Analyze the performance of your NGS pipeline
– routine performance monitoring (Research Use Only)
Product Overview
Format: FFPE (Formalin Fixed Paraffin Embedded)
Unit size: tailored
Expected DNA yield: tailored
Expected RNA yield: tailored
Thickness of one curl/cut: tailored µm
Mutations:
Make use of SensIDs own proprietary technology to develop FFPE reference materials with the mutation of your choice. Make use of your own cell line or choose one of ours.
Allelic frequency:
tailored
Storage: 2-8 °C
Expiration: stable for 24 months from date of manufacturing (as supplied)
Quality control (DNA)
Allelic Frequency (metrologically traceable): ddPCR (Bio-Rad)
Quantification (metrologically traceable): Fluorometric dsDNA measurement (Qubit)
DNA Quality: Agarose gel electrophoresis
Quality Control (RNA)
RNA Quantification: Fluorometric RNA measurement (Qubit)
Quality Control (other)
Cell Density:
1. Visual via microscopy
2. Calibrated measurement
Technical background
Derived from:
tailored cell line
Regulatory status:
Available in Research Use Only or CE-IVD grade including technical documentation.
This quality control product is ideally suited as reference material in clinical genomics workflows. In particular:
– Validation and development of extraction protocols
– control in sequencing protocols (e.g. Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES), Amplicon Sequencing) and PCR protocols
– Determination of the detectiont limit of a method
– Calibration and development of instruments and workflows in DNA processing (e.g. DNA fragmentation via acoustic shearing, enzymatic digestion or sonication)
– Analyze the performance of your NGS pipeline
– routine performance monitoring (Research Use Only)
Product Overview
Format: FFPE (Formalin Fixed Paraffin Embedded)
Unit size: tailored
Expected DNA yield: tailored
Expected RNA yield: tailored
Thickness of one curl/cut: tailored µm
Mutations:
Make use of SensIDs own proprietary technology to develop FFPE reference materials with the mutation of your choice. Make use of your own cell line or choose one of ours.
Allelic frequency:
tailored
Storage: 2-8 °C
Expiration: stable for 24 months from date of manufacturing (as supplied)
Quality control (DNA)
Allelic Frequency (metrologically traceable): ddPCR (Bio-Rad)
Quantification (metrologically traceable): Fluorometric dsDNA measurement (Qubit)
DNA Quality: Agarose gel electrophoresis
Quality Control (RNA)
RNA Quantification: Fluorometric RNA measurement (Qubit)
Quality Control (other)
Cell Density:
1. Visual via microscopy
2. Calibrated measurement
Technical background
Derived from:
tailored cell line